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KMID : 0359720180360030210
Journal of the Korean Neurological Association
2018 Volume.36 No. 3 p.210 ~ p.214
Unilateral Hypoglossal Neuropathy in Multifocal Acquired Demyelinating Sensory and Motor Neuropathy: Differential Diagnosis of Motor Neuron Disease
Yoo Sang-Kyeong

Kim Min-Ok
Kim Chang-Hun
Kim Young-Soo
Kim Soo-Kyoung
Kang Hee-Young
Choi Nack-Cheon
Kwon Oh-Young
Lim Byeong-Hoon
Park Kee-Hong
Abstract
Multifocal acquired demyelinating sensory and motor neuropathy (MADSAM) is a peripheral neuropathy characterized by multifocal weakness and associated sensory impairment. MADSAM is associated with multifocal persistent conduction block and other signs of demyelination. The incidence of cranial nerve involvement in MADSAM was recently reported to be approximately 15%. However, reports of hypoglossal neuropathy occurring in MADSAM are rare. Unilateral hypoglossal neuropathy in MADSAM is usually misdiagnosed as motor neuron disease. We report a patient with MADSAM presenting with tongue hemiatrophy.
KEYWORD
Peripheral demyelinating neuropathy, Motor neuron disease, Hypoglossal nerve diseases
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